Clinical outcome of subchromosomal events detected by whole-genome noninvasive prenatal testing

Clinical experience study with microdeletions • Positive predictive value (PPV) of microdeletions ranged from 60-100% • PPV for 22q11.2 deletion = 96.9-100% • False positive rate was 0.0017% • False negative rate and sensitivity could not be conclusively determined with this study