In addition to a comprehensive screening for more than 500 genetic disorders (Inheritest), we also offer screening for specific disorders, such as fragile X syndrome, the most common inherited form of intellectual disability, and a common known cause of autism.1
Fragile X syndrome is found among a variety of ethnic groups,2 and can occur in families with no history of inherited intellectual disability. Approximately one in 260 women3 and one in 800 males4 in the general population is a fragile X carrier. Since typically only a mother needs to be a carrier to pass on this disorder, the couple’s risk is higher than for cystic fibrosis.
Fragile X is the most common cause of inherited intellectual disability, which affects approximately 1 in 4,000 males and 1 in 8,000 females.1 Carrier screening for Fragile X will detect approximately 99% of individuals who are carriers of a mutation in the Fragile X gene and at risk of having a child with Fragile X syndrome.2
Approximately 1 in 260 women3 and 1 in 800 males4 in the general population is a carrier of fragile X syndrome. Fragile X syndrome occurs when a woman who carries a fragile X mutation, passes this mutation on to her child. Fragile X syndrome can be seen in families with a history of intellectual disability or in families without any such history.
Individuals are considered to have an increased risk to be fragile X carriers if they have:
At Labcorp, our focus is offering the right test at the right time to the right patient, which is why we offer two types of testing for fragile X.