PCOS (polycystic ovary syndrome) is the most common endocrine disorder affecting reproductive aged women and is one of the most common, but treatable, causes of infertility. For this reason, it is often diagnosed when women have trouble getting pregnant. However, PCOS may begin soon after the first menstrual period and is a lifelong metabolic syndrome. Did you know:
Several guidelines suggest using the Rotterdam criteria or variations of it for the diagnosis of PCOS. This is defined by the presence of two out of the three following criteria3:
In adolescents, both menstrual irregularity and hyperandrogenism are required, and ultrasound is not recommended for diagnosis. Guidelines also recommend certain testing to rule out other endocrine disorders with similar presentation, including thyroid disease, prolactin excess and non-classical congenital adrenal hyperplasia (CAH). In some women, additional diagnoses should be considered and ruled out, such as Cushing’s syndrome, androgen-secreting tumors and other disorders associated with androgen excess.4
Because women and children have lower levels of testosterone, it is important to utilize the more sensitive liquid chromatography/tandem mass spectrometry (LC/MS) methodology when measuring testosterone in these patients.5,6
At Labcorp, we believe that the right testing for every patient can improve care and outcomes. We understand that PCOS is a complex condition with numerous implications to consider throughout a woman’s lifetime. To assist providers in navigating diagnosis of PCOS, we offer a PCOS panel based on guideline recommendations.
Once diagnosed, assessment and management of reproductive, metabolic and psychological features is vital to patient care. Many significant comorbidities are associated with PCOS, and patient care may span across several types of healthcare providers and specialists.
Labcorp’s comprehensive test menu can help you care for your patients once they are diagnosed. Access fertility, diabetes, NASH, CVD testing and more as needed. Additionally, the PCOS Diagnostic Profile samples are retained for 60 days, allowing for add-on or repeat testing up to two months after the original blood draw date.
Labcorp’s Esoterix laboratories (formerly Endocrine Sciences and Colorado Coagulation) have more than 40 years of experience in performing specialized laboratory testing and a large team of scientists and physician specialists available for client consultation.