Labcorp is your source for information and diagnostic support as you help manage your symptomatic patients.
During their lifetime, the majority of women will have a vaginal infection, characterized by discharge, itching, burning or odor. With the availability of complementary and alternative therapies and over-the-counter medications for candidiasis, symptomatic women often seek these products before or in addition to an evaluation by a medical provider.1
Evaluation of patients with vaginitis symptoms should include a focused history. Patients may have difficulty distinguishing vulvar and vaginal symptoms. It is important to elicit information about the location of symptoms (vulva, vagina, anus) description of symptoms, and duration of symptoms. The clinician should inquire about the following to yield important insights into the likely etiology:2
In settings where pH paper, KOH and microscopy are unavailable, a broad range of clinical laboratory tests, described in the diagnosis section for each disease, can be used.1
According to the CDC 2021 Sexual Transmitted Treatment Guidelines
Vaginitis has a broad differential diagnosis, and successful treatment frequently rests on an accurate diagnosis. The most common cause of vaginitis include vulvovaginal candidiasis, bacterial vaginosis and trichomoniasis.2
For the past decade, our NuSwab testing portfolio has offered physicians a non-subjective, cost-effective and clinically relevant means to diagnose millions of symptomatic patients with vaginitis/vaginosis. Our profiles have been developed to maximize sensitivity and specificity, allow providers to detect the underlying cause of a woman’s BV-like symptoms and treat her accordingly.
NuSwab sensitivity/specificity - 96.9%/92.6%
BD Affirm sensitivity/specificity - 90.1%/67.6%
NuSwab sensitivity/specificity - 97.7%/93.2%
BD Affirm sensitivity/specificity - 58.1%/100%
NuSwab sensitivity - 98.1%
BD Affirm sensitivity - 46.3%
1. Sexually Transmitted Infections Treatment Guidelines, 2021. https://www.cdc.gov/std/treatment-guidelines/default.htm. Accessed July 29, 2021.
2. American College of Obstetricians and Gynecologists. Vaginitis in Nonpregnant Patients. ACOG Practice Bulletin No. 215.Obstet Gynecol. Vol 135, NO.1, January 2020.
3. CDC Bacterial Vaginosis (BV) Statistics, 2020. https://www.cdc.gov/std/bv/stats.htm. Accessed March 22, 2022.
4. Bacterial Vaginosis Survey – Patients & Healthcare Professionals, Harris Insights & Analytics Survey conducted September 14-29, 2017, (https://www.keepherawesome.com/bacterial-vaginosis); Accessed March 22, 2022.
5. Cartwright CP, Lembke BD, Ramachandran K, Body BA, Nye MB, Rivers CA, Schwebke JR. Comparison of Nucleic Acid Amplification Assays with BD Affirm VPIII for Diagnosis of Vaginitis in Symptomatic Women. J Clin Micro. Nov 2013;51(11):3694-3699.