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Lynch Syndrome - also known as hereditary non-polyposis colorectal cancer (HNPCC) - is a rare, inherited form of colon cancer that arises from mutations in DNA mismatch repair genes. Under normal conditions, DNA mismatch repair proteins repair mistakes in DNA. Lynch Syndrome is sometimes associated with other forms of cancer, including endometrial, ovarian, pancreas, stomach, small bowel, biliary, and urinary tract carcinomas.