Sulfate transporter-related osteochondrodysplasias

The sulfate transporter-related osteochondrodysplasias (STROs) are a group of inherited diseases characterized by short stature and short limbs, spine and joint abnormalities, and early-onset osteoarthritis. The STROs involves abnormalities in a protein that transports sulfate into cells where it is needed for the development of cartilage. The symptoms of STRO are due to the abnormal formation of cartilage and its conversion to bone. The four types of STRO are known as recessive multiple epiphyseal dysplasia, diastrophic dysplasia, atelosteogenesis type 2 (also known as de la Chapelle dysplasia or McAlister dysplasia), and achondrogenesis type 1B. View testing options