Cytogenetics Blood Chromosome Analysis

CPT 88230; 88262
Synonyms Karyotype; Routine G-Banding;

Test Details

Turnaround Time

7 - 14 days Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.


Evaluate congenital malformations, intellectual disability, growth restriction, infertility, cryptorchidism, hypogonadism, amenorrhea (primary), abnormal/ambiguous genitalia, recurrent miscarriage, Turner syndrome, Klinefelter syndrome, Down syndrome, or other suspected chromosomal disorders.

Specimen Requirements

Information on collection, storage, and volume


Whole blood


5-10 mL (adult); 2-5 mL (child - less for newborn)


Green-top (sodium heparin) tube

Storage Instructions

Maintain specimen at room temperature. Do not freeze.

Causes for Rejection

Hemolysis; specimen clotted; use of improper anticoagulant; frozen specimen


High concentrations of heparin are toxic. Do not collect small volumes in large vacutainers or add additional heparin to specimens.