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One kit. One best-in-class solution for combined prenatal testing.

Labcorp prenatal genetics combination kit

When it comes to prenatal testing, we understand that convenience and simplicity matter. Our new combination kit includes MaterniT® NIPS and Inheritest® Carrier Screen (or single-gene testing CFplus®), offering easy specimen handling and streamlined ordering.

Optimize patient care. Maximize effectiveness. 

 

Maternit NIPS

Broad prenatal screening coverage

  • Core trisomies, optional fetal sex/sex chromosome aneuploidies/microdeletions/genome-wide
  • GENOME-Flex – a unique NIPS high-risk pathway1-5
  • Patients: Average/high risk, singleton/twin/multiple gestations, high BMI, and IVF/ART
  • Aligns with medical society guidelines supporting prenatal screening for all pregnant women

Reliable results

  • Very low nonreportable rate, 0.9%6 overall, 2.08%7 drawn at 9 weeks, 2.4%8 patients that weigh 200-225 lbs, 2.66%9 multifetal pregnancies 
  • Mosaicism Ratio reporting identifies which positive results are more likely to be true positives10

Rapid prenatal screening results

  • 3-5 day turnaround time

Extensive experience

  • More than 2 million tests performed to date11 including twins, triplets and genome-wide
     
plus
Inheritest or CFplus

Comprehensive approach to disorder selection

  • Multiple carrier screening options - ranging from expanded panels with more than 500 genes to single-gene tests such as CFplus
  • Clinically relevant disorders selected using medical society guideline criteria

Continuum of care

  • Reproductive carrier screening
  • Focused partner testing through gene-specific sequencing to identify more at-risk pregnancies
  • Prenatal diagnosis to identify affected pregnancies

Rapid prenatal screening results

  • Turnaround time of around 2 weeks for most Inheritest Carrier Screen Panels** and 7-10 days for CFplus

Science and extensive experience

  • ~99% analytical sensitivity for most disorders12
  • Positive result confirmation according to medical society guidelines
  • Over 25 years of carrier screening experience

*Other single-gene tests available
** Turnaround time varies by test and panel. Visit labcorp.com/test-menu/search for details

Download your quick guide to
prenatal screening guidelines

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Have questions or ready to order?
 

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References

  1. Illumina. https://www.illumina.com/clinical/illumina_clinical_laboratory/verifi-prenatal-tests.html. Accessed August 15, 2018. 
  2. Natera. https://www.natera.com/panorama-test/clinical-information. Accessed August 15, 2018. 
  3. Counsyl. https://www.counsyl.com/services/prelude/clinical-info. Accessed August 15, 2018. 
  4. Progenity. https://progenity.com/tests/innatal. Accessed August 15, 2018. 
  5. Harmony. http://www.harmonytestusa.com/healthcare-professionals/providing-harmony. Accessed August 15, 2018
  6. Palomaki GE, Deciu C, Lambert-Messerlian GM, et al. DNA sequencing of maternal plasma to detect Down syndrome: An international clinical validation study. Genet Med. 2011;13(11): 913-920.
  7. Internal data 
  8. Wardrop J, McCullough R, Boomer T, et al. Maternal weight – impact on noninvasive prenatal testing (NIPT). Clinical poster presented at ACMG annual meeting, Florida 2016.
  9. Dyr B, Boomer T, Almasri EA, et al. A new era in aneuploidy screening: cfDNA testing in >30,000 multifetal gestations: Experience at one clinical laboratory. PLoS One. 2019;14(8):e0220979.
  10. Rafalko et al. Impact of Mosaicism Ratio on positive predictive value of cfDNA screening. Prenatal Diagnosis, 2020.
  11. Internal data
  12. Internal data